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Human Genetic Engineering confirmed

DrLeftover

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Chinese scientists genetically modify human embryos
Rumours of germline modification prove true — and look set to reignite an ethical debate.

22 April

In a world first, Chinese scientists have reported editing the genomes of human embryos. The results are published1 in the online journal Protein & Cell and confirm widespread rumours that such experiments had been conducted — rumours that sparked a high-profile debatelast month2, 3 about the ethical implications of such work.

In the paper, researchers led by Junjiu Huang, a gene-function researcher at Sun Yat-sen University in Guangzhou, tried to head off such concerns by using 'non-viable' embryos, which cannot result in a live birth, that were obtained from local fertility clinics. The team attempted to modify the gene responsible for β-thalassaemia, a potentially fatal blood disorder, using a gene-editing technique known as CRISPR/Cas9. The researchers say that their results reveal serious obstacles to using the method in medical applications.

"I believe this is the first report of CRISPR/Cas9 applied to human pre-implantation embryos and as such the study is a landmark, as well as a cautionary tale," says George Daley, a stem-cell biologist at Harvard Medical School in Boston, Massachusetts. "Their study should be a stern warning to any practitioner who thinks the technology is ready for testing to eradicate disease genes."

Some say that gene editing in embryos could have a bright future because it could eradicate devastating genetic diseases before a baby is born. Others say that such work crosses an ethical line: researchers warned in Nature2 in March that because the genetic changes to embryos, known as germline modification, are heritable, they could have an unpredictable effect on future generations. Researchers have also expressed concerns that any gene-editing research on human embryos could be a slippery slope towards unsafe or unethical uses of the technique.
http://www.nature.com/news/chinese-scientists-genetically-modify-human-embryos-1.17378
 

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Welcome to Offtopix 👋, Visitor

Off Topix is a well-established general discussion forum that originally opened to the public in 2009! We provide a laid-back atmosphere, and our members are down to earth. We have a ton of content, and fresh stuff is constantly being added. We cover all sorts of topics, so there's bound to be something inside to pique your interest. We welcome anyone and everyone to register and become a member of our awesome community.

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