How The Hell Is He Still Awake?

[Webster]

From the TV Tropes page for heavy metal legend Ozzy Osbourne....

http://www.indyposted.com/123988/scientists-say-ozzy-osbourne-is-a-genetic-mutant-are-you-surprised/

Ozzy Osbourne (Music) - TV Tropes

ALL ABOAAAARD! DESCRIBE THE PRINCE OF DARKNESS HERE! Born John Michael Osbourne on December 3, 1948 in Aston, Birmingham. Also known as Ozzy. Or the "Prince of Darkness", if you want. As one of the first Heavy Metal singersor maybe even the …

tvtropes.org

Immune to Drugs:
To the point where he had his genome mapped to figure out how on earth he's still alive. The Cambridge project that did so found several genes that allow him to metabolize opiates and alcohol far more efficiently than most humans. Basically, if almost anyone else did as many drugs as he did, they would have died a long time ago. His autobiography describes it best in a minor Crowning Moment of Funny, where Ozzy decided to have a colonoscopy done.

Regular Dose of Anesthetic:
-Ozzy: Is that the inside of my arsehole?
-Doctor: Why the hell aren’t you asleep?
-Ozzy: Dunno.
-Doctor: Don’t you feel groggy?
-Ozzy: Not really.
-Doctor: Not even a little bit?
-Ozzy: Nope.

Twice the Dose:
-Doctor: How are you feeling?
-Ozzy: Fine, thanks.
-Doctor: Jesus Christ, you’re still awake? I’m going to give you some more.
-Ozzy: Go on then.

Three Times the Dose:
-Doctor: How about now, Mr. Osbourne? Blink if you can hear me.
-Ozzy: Blink? Why can’t I just tell you?
-Doctor: That’s impossible! You’re not human!
-Ozzy: How can I fall asleep during this? Any minute now you’re going to find some long-lost cufflinks up there, or maybe an old watch, or a pair of Sharon’s tights.